本课程旨在扩展对生物化学II级课程中蛋白质结构和功能的讨论, 并利用该知识来了解分子生物学的某些基本过程。该课程涵盖两个主要主题：蛋白质结构和功能：主题包括-不同种类蛋白质的结构和功能, 蛋白质折叠, 靶向蛋白质降解, 新疗法的开发, 分子相互作用和识别。基因表达的控制：主题包括；基因回路和合成生物学；染色质结构及其在转录过程中的重塑；基因启动子上转录因子和RNA聚合酶复合物的募集和组装；使用“设计基因”和合成转录因子人工操纵基因表达；真核生物mRNA的合成, 加工, 修饰, 稳定性和翻译, 以及对这些过程的操纵以影响选择性基因表达。本课程将讲座和辅导与基于前沿研究的实践练习相结合, 以补充讲座材料。
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